First Peer-Reviewed Study by Mammoth Biosciences of COVID-19 Test
Mammoth Biosciences
Mammoth Biosciences is an SF-based CRISPR diagnostic startup company. Today, it has published a peer-reviewed study, which reveals the validation of using the testing procedure to determine the presence of coronavirus in the patients. The study is published in Nature and shows that the performance on par with the prevailing PCR-based molecular analyzing, which is currently approved by the FDA to carry on the test to determine coronavirus in patients.
The DETECTR platform of Mammoth Biosciences is planned to have benefits over the conventional testing procedure in various ways including the reconfigurability to determine the virus since it utilizes the CRISPR to focus on a specific genetic sequence and enable a cleavage, which efficiently acts as a warning for diagnostic equipment. Generally, in a similar way, the CRISPR allows the researchers to focus on a specific portion of the DNA for alteration or removal with precision.
| VPN | Ranking | Pros | Website |
|---|---|---|---|
 | Ranked #1 | Exceptionally fast VPN speeds No user web logs & no IP address leaks Unblocks Netflix, BBC iPlayer, Disney+ & more Unrestricted torrenting & P2P traffic Over 3,000 VPN servers in 94 countries Easy to use apps & VPN browser extensions | Visit |
 | Ranked #2 | Very fast same-country speeds No logs & no IP, DNS or WebRTC leaks Works with Netflix, BBC iPlayer, Disney+, etc. Huge server network (over 5,500 servers in 58 countries) Torrenting P2P allowed on many servers Simple custom VPN apps for range of platforms | Visit |
 | Ranked #3 | Very fast & reliable VPN speeds Doesn't keep user logs & doesn't leak Dedicated streaming servers for Netflix & BBC iPlayer Optimized VPN servers optimized for P2P traffic Biggest server network (6,200+ servers across 90 countries) Automatic public WiFi protection | Visit |
 | Ranked #4 | Impressive VPN speeds No-logs policy & verified IP leak protection Works with Netflix All VPN servers allow torrenting traffic Best VPN app for Fire TV Stick Over 1,300 VPN servers in 50 countries | Visit |
 | Ranked #5 | Consistently fast VPN speeds No logging & no IP, DNS & WebRTC leaks Works with Netflix, BBC iPlayer & more No limits on torrenting traffic 7,000 individual IP addresses in 59 countries Very simple & user-friendly VPN apps | Visit |
 | Ranked #6 | No Logging Free option Very fast Works with Netflix | Visit |
 | Ranked #7 | Very fast local speeds Verified no-logs privacy policy Unblocks US Netflix & BBC iPlayer Unlimited torrenting & P2P file sharing Advanced & customizable encryption Cheap price | Visit |
 | Ranked #8 | No-logs policy & No IP, DNS, & WebRTC leaks Chameleon protocol works in China Torrenting & P2P on all servers Advanced features including kill switch Easy-to-use apps for PC, Mac, iOS, Android, router & smart TV First party server network & DNS across 64 countries | Visit |
 | Ranked #9 | Impressive download speeds Desktop & mobile apps are free of IP/DNS/WebRTC leaks Paid version works with Netflix & torrenting Fairly big VPN server network: 82 countries User-friendly VPN apps for popular devices | Visit |
 | Ranked #10 | Excellent budget price Unblocks Netflix & BBC iPlayer Supports torrenting Lots of advanced features Privacy-friendly jurisdiction Unlimited simultaneous devices | Visit |
The Testing and Procedure
The diagnostic of Mammoth allows the programmable, targeted matching with reference string by leading to confirmation that the RNA of this virus is present in the patient. The test, which the Mammoth is developing, has shown validated utilization under two weeks. The researchers claim that the platform is planned from ground up for quick reconfigurability to locate the virus threats. This test can deliver the result within 45 minutes, and the result will be delivered via “lateral flow strip”. It is the same sort of read-out you see with the pregnancy test that you do in your home.
It is now relatively easier to interpret. DETECTR doesn’t need a lab setting to provide results. Instead, it can be conducted with the portable heat blocks, merged with available standard reagents.
The study included 36 patients with confirmed coronavirus infections, and 42 patients had other sorts of viral respiratory problems. Importantly, the test showed 95% positive diagnostic accuracy.
